CA9 抗体
Quick Overview for CA9 抗体 (ABIN6297759)
抗原
See all CA9 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Mouse anti-Human/Horse CAIX Antibody Carbonic Anhydrase IX [IHC only]
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特异性
- Cell surface and cytoplasmic
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纯化方法
- The microsomal fraction of human renal cortical tissue homogenate was used as the immunogen for this Carbonic Anhydrase IX / CAIX antibody.
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免疫原
- The microsomal fraction of human renal cortical tissue homogenate was used as the immunogen for this Carbonic Anhydrase IX / CAIX antibody.
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应用备注
- Prediluted format : incubate for 30 min at RT (2)
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限制
- 仅限研究用
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缓冲液
- Prediluted in 1X PBS ( pH 7.4) with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, For IHC use only
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- CA9 (Carbonic Anhydrase IX (CA9))
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别名
- Carbonic anhydrase 9
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背景
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Target Description: This antibody recognizes a glycoprotein of ~200 kDa, identified as renal cell carcinoma protein, carbonic anhydrase IX / CAIX, or gp200. Its epitope resides in the carbohydrate domain of the protein. The CAIX antibody shows no significant cross-reactivity with other carbohydrate determinants, such as the Lewis blood group antigens, epithelial membrane antigen, HMFG, and AB blood group antigens. In normal kidney, CAIX is localized along the brush border of the pars convoluta and pars recta segments of the proximal tubule, as well as focally along the luminal surface of Bowman's capsule adjoining the outgoing proximal tubule. Reportedly, it is expressed by 93 % of primary and 84 % of metastatic renal cell carcinomas. This CAIX antibody may be useful in the investigations of carcinomas of proximal nephrogenic differentiation, especially those showing tubular differentiation.
Gene Symbol: CA9///G250///MN
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基因ID
- 768
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UniProt
- Q16790
抗原
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